Turk Kardiyol Dern Ars. 2016; 44(4): 342-345 | DOI: 10.5543/tkda.2015.26511
DOCK8 deficiency in a boy who presented with a giant aortic aneurysm between aortic root and iliac bifurcation
Türkan Patıroğlu1, Himmet Haluk Akar1, Mehmet Sait Doğan2, Kazım Üzüm31Erciyes University School Of Medicine, Department Of Pediatric Immunology, Kayseri, Turkey
2Erciyes University School Of Medicine, Department Of Pediatric Radiology, Kayseri, Turkey
3Erciyes University School Of Medicine, Department Of Pediatric Cardiology, Kayseri, Turkey
Summary– Dedicator of cytokinesis 8 protein (DOCK8) deficiency is an autosomal recessive, inherited form of hyper-immunoglobulin E (hyper-IgE) syndrome, characterized by persistent cutaneous viral infections, elevated IgE, eosinophilia, and allergic manifestations. The case of a 10-year-old boy who presented with giant aortic aneurysm between the aortic root and iliac bifurcation is described in the present report. Aortic aneurysm of this size has not yet been reported.
Keywords: Aortic aneurysm, DOCK8 protein, hyper IgE syndrome.
How to cite this article
Türkan Patıroğlu, Himmet Haluk Akar, Mehmet Sait Doğan, Kazım Üzüm. DOCK8 deficiency in a boy who presented with a giant aortic aneurysm between aortic root and iliac bifurcation. Turk Kardiyol Dern Ars. 2016; 44(4): 342-345
Corresponding Author: Himmet Haluk Akar, Türkiye
Manuscript Language: English