Archives of the Turkish Society of Cardiology
Prevalence of Hypertension and Blood Pressure Data in Turkey: Systematic Review, Meta-analysis and Meta-regression of Epidemiological Studies on Cardiovascular Risk Factors [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. Ahead of Print: TKDA-15679 | DOI: 10.5543/tkda.2018.15679

Prevalence of Hypertension and Blood Pressure Data in Turkey: Systematic Review, Meta-analysis and Meta-regression of Epidemiological Studies on Cardiovascular Risk Factors

Mustafa Kılıçkap1, Cem Barçın2, Hüseyin Göksülük1, Doruk Karaaslan3, Necla Özer4, Meral Kayıkçıoğlu5, Dilek Ural3, Mehmet Birhan Yımaz6, Adnan Abacı7, Mustafa Arıcı8, Bülent Altun8, Lale Tokgözoğlu4, Mahmut Şahin9
1Ankara University School of Medicine, Cardiology Dept., Ankara, Turkey
2University of Health Sciences, Gulhane Educational and Research Hospital, Cardiology Dept, Ankara, Turkey
3Koc University Faculty of Medicine, Istanbul, Turkey
4Hacettepe University Faculty of Medicine, Cardiology Dept., Ankara, Turkey
5Ege University Faculty of Medicine, Cardiology Dept., Izmir, Turkey
6Cumhuriyet University Faculty of Medicine, Cardiology Dept., Sivas, Turkey
7Gazi University Faculty of Medicine, Cardiology Dept., Ankara, Turkey
8Hacettepe University Faculty of Medicine, Nephrology Dept., Ankara, Turkey
9Ondokuz Mayıs University Faculty of Medicine, Cardiology Dept., Samsun, Turkey


OBJECTIVE
We performed a systematic review and meta-analysis of epidemiological studies conducted in Turkey to assess the latest profile and temporal changes in cardiovascular (CV) risk factors. Here, we present the data for hypertension (HT) and blood pressure (BP).

METHODS
Ovid Medline, Web of Science Core Collection and ULAKBIM were searched for epidemiological studies conducted in Turkey during the last 15 years. Also, web pages of Ministry of Health, Turkish Statistical Institution, Cardiology, Nephrology and Endocrinology Associations were searched for appropriate studies. Regional studies were excluded. Included studies were assessed with a bias score that is developed by our team, then categorized as low or high risk of bias studies. Crude values of HT prevalence and BP were pooled using random effects model. Meta-regression was performed to assess the heterogeneity and the temporal changes.

RESULTS
Agreement between two authors for the selection and bias scoring of the studies was perfect (Kappa ≥0,95). There were 7 (n=73218) studies giving HT prevalence, and 8 (n=75879) studies giving BP data. Heterogeneity between the studies was high. Meta-analysis of the studies with low risk of bias, which have been conducted between 2003 and 2012, showed that crude prevalence of HT is higher in women, but BP levels were similar in both sex; HT prevalence and BP decreased between 2003-2012; however number of hypertensives stabilized around 15 million, and number of uncontrolled hypertensives, despite some decrease, was around 11 million.

CONCLUSION
Despite some improvement, HT is still an important public health problem in Turkey.

Keywords: Hypertension, prevalence, blood pressure, meta-analysis, meta-regression, epidemiology

How to cite this article


Corresponding Author: Mustafa Kılıçkap, Türkiye
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