Turk Kardiyol Dern Ars. Ahead of Print: TKDA-12844 | DOI: 10.5543/tkda.2018.12844
Predictive Power of Different Obesity Measures for the Presence of Diastolic Dysfunction
Yalın Tolga Yaylalı1
, Güzin Fidan-yaylalı2
, Beray Can3
, Hande Şenol4
, Mehmet Kılınç1
, Mustafa Yurtdaş51
Department of Cardiology, Pamukkale University, Denizli, Turkey2
Department of Endocrinology and Metabolic Diseases, Pamukkale University, Denizli, Turkey3
Department Of Internal Medicine, Van Training And Research Hospital, Van, Turkey4
Department Of Biostatistics, Pamukkale University, Denizli, Turkey5
Department Of Cardiology, Balikesir Ozel Sevgi Hospital, Balikesir, Turkey
OBJECTIVE Body mass index (BMI) and waist circumference (WC) as measures of obesity have some limitations. This study aimed to evaluate whether one measure could predict the presence of diastolic dysfunction (DD) more accurately than the other measures.
METHODS Ninety-one obese subjects without any other risk factors for DD were prospectively enrolled. Echocardiographic examination was performed. DD was defined and categorized according to the recent guidelines for heart failure. Subjects were divided into 2 groups according to the presence of DD. Weight, height, and WC were measured; BMI and WHR were calculated; and a body shape index (ABSI) was calculated as WC/(BMI2/3height1/2). We examined the associations of ABSI, BMI, WHR, and WC with the presence of DD by logistic regression analyses. Analysis of Covariance was used to examine the differences.
RESULTS WC and BMI were significantly increased in subjects with DD (p: 0,049 and 0,051, respectively). Increased BMI, WC, and WHR increased the risk of the presence of DD [BMI-DD: odds ratio (OR) = 1.096, p: 0.024; WC-DD: OR = 1.059, p: 0.007; WHR-DD: OR = 2.363, p: 0.007]. After adjustment for age and sex, only BMI continued to be significantly associated with DD (p: 0.031). ABSI was not associated with DD.
CONCLUSION After adjustment for age and sex, BMI was the only predictor of DD in obesity. Despite its limitations, BMI could still be a potentially more accurate measure of DD among different obesity measures.
a body shape index, body mass index, diastolic dysfunction, waist circumference, waist to hip ratio, obesity
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Corresponding Author: Yalın Tolga Yaylalı, Türkiye