Turk Kardiyol Dern Ars. 2016; 44(2): 114-122 | DOI: 10.5543/tkda.2016.09451
Assessment of myocardial performance index and its association with aortic elasticity in patients with ascending aortic aneurysm
Ahmet Oytun Baykan1
, Mustafa Gür2
, Gülhan Yüksel Kalkan1
, Armağan Acele1
, Taner Şeker1
, Ömer Şen1
, Abdürrezzak Börekçi2
, Mevlüt Koç1
, Murat Çaylı31
Department of Cardiology, Adana Numune Training and Research Hospital, Adana, Turkey2
Department of Cardiology, Kafkas University Faculty of Medicine, Kars, Turkey3
Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakir, Turkey
OBJECTIVE Ascending aortic aneurysms (AAA) are a leading cause of morbidity and mortality. Nevertheless, their effects on global cardiac functions are yet to be fully understood. Myocardial performance index (MPI) has been widely used to quantitatively assess myocardial functions. The aim of this study was to evaluate left ventricular (LV) functions in patients with AAA using tissue Doppler (TD) echocardiography and MPI in addition to conventional echocardiographic methods.
METHODS Fifty patients with AAA (33 men, 17 woman; mean age 55.5±7.90 years) were included, and 106 patients without aortic dilatation (mean age 54.1±8.18 years) were included as the control group. LV systolic and diastolic functions were analyzed using 2-dimensional, M-mode, and TD echocardiography.
RESULTS Patients with AAA had significantly higher MPI (0.5±0.04 vs 0.4±0.05, p<0.001), TD-MPI (0.5±0.02 vs 0.4±0.03, p<0.001), and reduced aortic elasticity, as indicated by reduced aortic distensibility (AD) (1.7±1.27 vs 3.1±1.25, p<0.001). Multivariate linear regression analysis showed that TD-MPI was independently correlated with reduced aortic distensibility (B=-0.006, p=0.019, 95% confidence interval,-0.011 to -0.001).
CONCLUSION MPI and TD-MPI indicated impairment of global cardiac functions in patients with AAA, which may be attributed to reduced aortic elasticity.
Aortic aneurysm, myocardial performance index; tissue Doppler echocardiography
How to cite this article
Ahmet Oytun Baykan, Mustafa Gür, Gülhan Yüksel Kalkan, Armağan Acele, Taner Şeker, Ömer Şen, Abdürrezzak Börekçi, Mevlüt Koç, Murat Çaylı. Assessment of myocardial performance index and its association with aortic elasticity in patients with ascending aortic aneurysm. Turk Kardiyol Dern Ars. 2016; 44(2): 114-122
Corresponding Author: Ahmet Oytun Baykan, Türkiye