ISSN 1016-5169 | E-ISSN 1308-4488
Archives of the Turkish Society of Cardiology
pdf
Gallopamil Treatment in Chronic Stable Angina Pectoris: A Double Blind, Placebo-Controlled Study [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 1990; 18(3): 176-181

Gallopamil Treatment in Chronic Stable Angina Pectoris: A Double Blind, Placebo-Controlled Study

A.Eftal YÜCEL1, Ferhan ÖZMEN1, Mehmet KABUKÇU1, Haldun MÜDERRİSOĞLU1, Sırrı KES1, Aydın KARAMEHMETOĞLU1

Antiangial effect of gallopamil was investigated as a double blind, placebo-controlled study in 14 patients with chronic stable angina pectoris (10 men, 4 women, mean age 53.8±9.1). Ergometric exercise stress test was performed in all patients before and after two-week drug or placebo periods. Number of anginal attacks per week and nitrate consumption declined after gallopamil when compared to placebo (81% and 79%; p<0.001 and p<0.01). Resting heart rate, systolic and diastolic blood pressures statistically significantly diminished after gallopamil therapy (p<0.005 and p<0.01). While resting ratepressure product walues were less than that of placebo period in gallopamil period, exercise tolerance increased 36% after gallopamil treatment compared with placebo. Also the amount of ST segment depression significantly decreased in patients receiving gallopamil (p<0.001). It was concluded that, gallopamil is an effective agent in the treatment of chronic stable angina pectoris.

Keywords: Gallopamil, chronic stable angina, exercise testing

How to cite this article
A.Eftal YÜCEL, Ferhan ÖZMEN, Mehmet KABUKÇU, Haldun MÜDERRİSOĞLU, Sırrı KES, Aydın KARAMEHMETOĞLU. Gallopamil Treatment in Chronic Stable Angina Pectoris: A Double Blind, Placebo-Controlled Study. Turk Kardiyol Dern Ars. 1990; 18(3): 176-181
Manuscript Language: Turkish


Journal Metrics

Journal Citation Indicator: 0.18
CiteScore: 1.1
Source Normalized Impact
per Paper:
0.22
SCImago Journal Rank: 0.348

Quick Search



Copyright © 2024 Archives of the Turkish Society of Cardiology



Kare Publishing is a subsidiary of Kare Media.