Turk Kardiyol Dern Ars. Ahead of Print: TKDA-88054 | DOI: 10.5543/tkda.2019.88054
Relationship Between SYNTAX Score and Myocardial Viability in Ischemic Cardiomyopathy
, ahmet seyfeddin gurbuz2
, Cevat Kirma31
Department Of Cardiology, Haseki Training And Research Hospital, Istanbul, Turkey2
Department Of Cardiology, Necmettin Erbakan University, Meram Faculty Of Medicine, Konya, Turkey3
Department of Cardiology, Kartal Koşuyolu Heart Education and Research Hospital, Istanbul, Turkey.
Background and aim: SYNTAX score is not only a measure of severity of coronary artery disease, but also complexity. We aimed to evaluate the relationship between SS and myocardial viability/non-viability assessed with positron emission tomography (PET) in patients with ischemic cardiomyopathy. Keywords:
Materials and methods: 107 patients with ischemic cardiomyopathy who had undergone PET were enrolled in this study. Patients were divided into two groups according to the presence of viable myocardium: 21 patients who had non-viable myocardium (only scar tissue) and 86 patients who had viable myocardium. SS were analyzed.
RESULTS Patients with non-viable myocardium have significantly higher levels of SS (14.1 ± 5.2 vs 17.6 ± 3.7) (p=0.004). Point biserial correlation showed that presence of myocardial non-viability mildly correlated with higher SS (rpb = -0.28, p: 0.004). In multivariate logistic regression analysis, SS [odds ratio (OR) = 1.164, 95% confidence interval (CI) 1.044 1.297, p=0.006] was identified as the sole independent predictor of myocardial non-viability. In ROC analysis, a cut-point of 16 identified patients with non-viable myocardium (area under curve (AUC) = 0.71, 95% CI 0.61 - 0.82). SS greater than 16 demonstrated a sensitivity of 76.2% and a specificity of 61.6%.
CONCLUSION The present study showed that SYNTAX score is associated with the presence of non-viable myocardium in ischemic cardiomyopathy.
cardiomyopathy, positron emission tomography, SYNTAX score, viability
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Corresponding Author: Semi Ozturk, Türkiye