The association of left ventricular mass index with coronary collateral circulation in patients with chronic total occlusion [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. Ahead of Print: TKDA-60497 | DOI: 10.5543/tkda.2018.60497

The association of left ventricular mass index with coronary collateral circulation in patients with chronic total occlusion

Mehmet Serkan Çetin1, Elif Hande Özcan Çetin2, Kadir Ocak2, Özlem Özcan Çelebi2, Dursun Aras2, Ahmet Temizhan2, Sinan Aydoğdu2
1TOBB-ETU University, Faculty of Medicine, Cardiology Clinic, Ankara/TURKEY
2Turkey Yuksek Ihtisas Training and Research Hospital, Cardiology Department, Ankara/TURKEY

Left ventricular hypertrophy predisposes myocardium to ischemia by means of several mechanisms. Left ventricular mass index (LVMI) is used as a readily-available and reliable measurement of left ventricular hypertrophy. Besides, left ventricular remodeling can be categorized with this parameter. In this study, we hypothesized that left ventricular hypertrophy might augment coronary collateralization in patients with chronic total occlusion (CTO) and aimed to investigate the association between LVMI and collateral formationin CTO. As a secondary goal, we aim to determine which specific left ventricular geometric type or types may be associated with collateral presence.

We included 305 patients with CTO and categorized into four Rentrop Grade groups.

LVMI showed a linear incremental trend towards ascending Rentrop Groups. In the ROC curve, the likelihood of a cut-off value 100.1 g / m2 to accurately differentiate patients with collaterals from without collaterals with 68.5% sensitivity and 68.6% specificity was 75.8%.One gram/m 2 increase of LVMI was associated with a 7.5% increased likelihood of collateral development. Comparing with normal geometry, presence of eccentric hypertrophy was associated with 6.7 times higher odds of coronary collateral presence.

In this study, we have shown that increased LVMI predicts the coronary collateral presence. Furthermore, having a geometric type of eccentric hypertrophy increases the likelihood of coronary collaterals more than other geometries. This finding pronounced that besides the left ventricular wall thickness, hypertrophy type was also decisive in predicting collateral presence.

Keywords: Coronary collateral circulation, left ventricular hypertrophy, left ventricular mass index

How to cite this article

Corresponding Author: Elif Hande Özcan Çetin, Türkiye
© Copyright 2018 Archives of the Turkish Society of Cardiology
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