Assessment of Cardiac Functions in Leprosy Patients by Echocardiography [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 1993; 21(5): 293-297

Assessment of Cardiac Functions in Leprosy Patients by Echocardiography

Y.Emir DÖNDER1, Oğuz AYHAN1, Y.Ali DEMİR1, Ahmet YILDIRIM1, Ramiz ÇOLAK1, Coşkun YILDIZ1, Sami AYHAN1, NADİ ARSLAN1

Cardiac and peripheral hemodynamics of 30 leprosy patients (22 men, 8 women, average 47±2 years) were investigated by using B-mode, M-mode, and continuous Doppler echocardiograms and compared with a control group (CG) which consisted of 20 healthy individuals (15 men, 5 women, average 45±2 years). The patients had been admitted to a local lepra hospital but in whom the lepra treatment had been discontinued 1-20 years previously. They were considered by dermatologists as having lepra sequelaer. In leprosy patients it was observedthat, as compared to the CG, left ventricular diastolic dimension was hugher (46.63±0.59 mm, 44.35±1.17 mm, p<0.05), early diastolic peak flow velocity (EVP) lower (62.86±1.74 cm/sec, 67.90±2.39 cm) sec, p<0.05), late diastolic peak flow velocity (AVP) was elevated (68.13±2.52 cm/sec, 61.75±2.33 cm/sec, p<0.05), E/A ratio diminished (0.95±0.04, 1.12±0.05, p<0.01), early diastolic mean flow velocity (EVM) was decreased (12.16±0.54 cm/sec, 13.50±0.51 cm/sec, p<0.05), late diastolic mean flow velocity (AVM) increased (13.73±0.43 cm/sec, 11.45±0.61 cm/sec, p<0.005), atrial index raised (0.53±0.01, 0.45±0.01, p<0.0005), EVM integral decreased (9.50±0.48 cm, 11.21±0.50 cm, p<0.025), AVM integral higher (10.71±0.41 cm, 9.50±0.55 cm, p<0.05), and EVM integral/AVM integral ratio was decreased (0.89±0.03, 1.20±0.03, p<0.0005). Thus, left ventricular diastolic function parameters were impaired, but parameters of systolic and peripheral hemodynamics were not affected in leprosy patients.

Keywords: Leprosy, cardiac function, echocardiography

How to cite this article
Y.Emir DÖNDER, Oğuz AYHAN, Y.Ali DEMİR, Ahmet YILDIRIM, Ramiz ÇOLAK, Coşkun YILDIZ, Sami AYHAN, NADİ ARSLAN. Assessment of Cardiac Functions in Leprosy Patients by Echocardiography. Turk Kardiyol Dern Ars. 1993; 21(5): 293-297
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