The relationship between visible thrombus aspiration material with no-reflow and in-hospital mortality ratio in patients with anterior ST elevation myocardial infarction treated with primary percutaneous coronary intervention [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. Ahead of Print: TKDA-49940 | DOI: 10.5543/tkda.2019.49940

The relationship between visible thrombus aspiration material with no-reflow and in-hospital mortality ratio in patients with anterior ST elevation myocardial infarction treated with primary percutaneous coronary intervention

Taner Şeker1, Caner Türkoğu2, Oğuz Akkuş3, Mustafa Gür1
1Department of Cardiology, Health Sciences University, Adana Health Practice and Research Center, Adana, Turkey.
2Department of Cardiology, Malatya Training and Research Hospital, Malatya, Turkey.
3Department of Cardiolgy, Mustafa Kemal Univiersity, Hatay, Turkey.

The relationship between visible thrombus aspiration material with no-reflow and in-hospital mortality ratio in patients with anterior ST elevation myocardial infarction treated with primary percutaneous coronary intervention
Running Head: Thrombus aspiration and no-reflow


OBJECTIVES
Benefit of intracoronary thrombus aspiration (TA) during primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) is not fully clear yet. In this study we aim to investigate clinical impact of visible thrombus aspiration material.

METHODS
We prospectively included 295 patients with TIMI 0 or I flow anterior STEMI. Manual TA devices were used for TA before PCI. The patients were divided into two group; visible thrombus aspiration group (VTA) and non-visible thrombus aspiration (non-VTA). No-reflow was defined as TIMI grade 0, 1 and 2 flows or TIMI grade 3 with myocardial blush grade 0 and 1. The primary end point was the occurrence of no-reflow.

RESULTS
Visible thrombus aspiration was achieved 178 (60.3%) of patients. No- reflow was found significantly lower in VTA group (p< 0,001). Ejection fraction (EF) and ST-segment resolution were higher, and in-hospital mortality, Killip class II-IV and Post-pPCI TIMI frame count were lower in VTA group (p< 0.05 for all).


CONCLUSIONS
Visible thrombus aspiration predicts lower rate of in hospital mortality and no-reflow in patients with anterior STEMI undergoing pPCI.
Key words: thrombus aspiration, no reflow, mortality, STEMI

Keywords: thrombus aspiration, no reflow, mortality, STEMI

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Corresponding Author: Taner Şeker, Türkiye
© Copyright 2019 Archives of the Turkish Society of Cardiology
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