Turk Kardiyol Dern Ars. 2019; 47(2): 95-102 | DOI: 10.5543/tkda.2019.49940
The relationship between visible thrombus aspiration material with no-reflow and in-hospital mortality ratio in patients with anterior ST-elevation myocardial infarction treated with primary percutaneous coronary intervention
, Caner Türkoğlu2
, Oğuz Akkuş3
, Mustafa Gür11
Department of Cardiology, Health Sciences University, Adana Health Practice and Research Center, Adana, Turkey2
Department of Cardiology, Malatya Training and Research Hospital, Malatya, Turkey3
Department of Cardiolgy, Mustafa Kemal Univiersity Faculty of Medicine, Hatay, Turkey
OBJECTIVE The benefit of intracoronary thrombus aspiration (TA) during primary percutaneous coronary intervention (pPCI) in patients with ST-segment elevation myocardial infarction (STEMI) is not yet fully clear. The aim of this study was to investigate the clinical impact of visible thrombus aspiration (VTA) material.
METHODS A total of 295 patients with a Thrombolysis in Myocardial Infarction (TIMI) flow score of 0 or 1 after an anterior STEMI were included in the study. Manual TA devices were used before performing PCI. The patients were divided into 2 groups: (1) visible thrombus aspiration (VTA) group and (2) non-visible thrombus aspiration (non-VTA) group. No-reflow was defined as TIMI grade 0, 1, or 2 flow, or TIMI grade 3 with
a myocardial blush of grade 0 or 1. The primary endpoint was the occurrence of no-reflow.
RESULTS VTA was retrieved in 178 (60.3%) of the patients. A no-reflow determination was significantly less frequent in the VTA group (p<0.001). The ejection fraction and ST-segment resolution values were higher, and the in-hospital mortality, Killip class II-IV rating, and post-pPCI TIMI frame count were lower in the VTA group (p<0.05 for each).
CONCLUSION VTA predicted a lower rate of in-hospital mortality and no-reflow in patients with anterior STEMI who underwent pPCI.
Mortality, no-reflow; ST-segment elevation myocardial infarction; thrombus aspiration.
How to cite this article
Taner Şeker, Caner Türkoğlu, Oğuz Akkuş, Mustafa Gür. The relationship between visible thrombus aspiration material with no-reflow and in-hospital mortality ratio in patients with anterior ST-elevation myocardial infarction treated with primary percutaneous coronary intervention. Turk Kardiyol Dern Ars. 2019; 47(2): 95-102
Corresponding Author: Taner Şeker, Türkiye