Improvement of Libman-Sacks endocarditis after combination of warfarin and immunosuppressive therapy [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. Ahead of Print: TKDA-29213 | DOI: 10.5543/tkda.2019.29213

Improvement of Libman-Sacks endocarditis after combination of warfarin and immunosuppressive therapy

Mehmet Rasih Sonsöz1, Rukiye Dilara Tekin2, Ahmet Gül2, Zehra Buğra1, Dursun Atılgan1
1Department of Cardiology, Istanbul University Istanbul Faculty of Medicine, Istanbul, Turkey
2Department of Rheumatology, Istanbul University Istanbul Faculty of Medicine, Istanbul, Turkey

The antiphospholipid syndrome (APS) is a clinical entity composed of arterial or venous thrombotic events or pregnancy-associated complications in the presence of autoantibodies against negatively charged phospholipids. This syndrome is often associated with systemic autoimmune diseases such as systemic lupus erythematosus(SLE). Libman-Sacks endocarditis is a form of non-bacterial thrombotic endocarditis and is infrequently seen in APS. There is a paucity of data documenting the echocardiographic response of APS valve disease to medical treatment. We hereby present an unusual case of a young female with SLE and APS who had chorea and non-bacterial thrombotic aortic valve endocarditis, in which improvement of vegetations was evident on echocardiography after combination of warfarin and immunosuppressive therapy.

Keywords: antiphospholipid syndrome, immunosuppressive therapy, Libman-Sacks endocarditis, systemic lupus erythematosus, warfarin

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Corresponding Author: Mehmet Rasih Sonsöz, Türkiye
© Copyright 2019 Archives of the Turkish Society of Cardiology
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