Turk Kardiyol Dern Ars. Ahead of Print: TKDA-18562 | DOI: 10.5543/tkda.2018.18562
Impaired Oscillometric Arterial Stiffness Parameters in Patients with Coronary Artery Ectasia
, Gökhan Alıcı, Samir Allahverdiyev, Ömer Genç, Ahmet Oytun Baykan, Süleyman Özbiçer, Mevlüt Koç
University of Health Sciences Adana Numune Training and Research Hospital, Department of Cardiology, Adana
OBJECTIVE We aimed to investigate the oscillometric measurements of elastic properties of the aorta in patients with isolated coronary artery ectasia (CAE).
METHODS This study included 137 patients (92 men and 45 women; mean age: 60.8 ±11.7 years) who underwent coronary angiography for the investigation of ischemic heart disease. The patients were divided into three groups; the first group consisted of 51 patients with CAE, the second group consisted of 36 patients with coronary artery disease (CAD), and the third group consisted of 50 patients with normal coronary arteries. Aortic stiffness (AS) measurements, including pulse wave velocity (PWV) and augmentation index (AIx), were measured by the oscillometric method.
RESULTS Mean PWV was significantly higher in the CAE group as compared with the CAD and control groups (9.1±2.3 vs. 8.2±1.3 and 8.0±1.6, p=0.008), whereas median AIx was significantly lower in the CAE group as compared with the CAD and control groups (10.0 (-3.0-63.0) vs. 15.5 (-2.0-57.0) and 21.5 (-1.0-45.0), p=0.010). Multinomial logistic regression analysis demonstrated that gender, hypertension, high-density lipoprotein cholesterol level, PWV and AIx were independently associated with CAE.
CONCLUSION The oscillometric elastic properties of the aorta, including PWV and AIx, are impaired in patients with CAE.
Coronary ectasia, arterial stiffness, pulse wave velocity, augmentation index
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Corresponding Author: Alaa Quisi, Türkiye