Serum Transferrin Saturation and Ferritin Level as a Risk Factor in Coronary Artery Disease [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 1998; 26(3): 142-144

Serum Transferrin Saturation and Ferritin Level as a Risk Factor in Coronary Artery Disease

Abdurrahman OĞUZHAN1, Halil Lütfi KISACIK1, Koray GÜRSEL1, Kurtuluş ÖZDEMİR1, Selime AYAZ2, İsmet HİSAR1, Ahmet AVCI1, Siber GÖKSEL1
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Epidemiologic studies have shown that serum iron can be a risk factor for coronary artery disease (CAD). The relation of serum ferritin !eve! and transferrio saturation with CAD was investigatcd in this study. Four-hundred male patients (mean age 56±4) who were hospitalized for coronary angiography in our clinic were included in this study. Paı ients were divided into two groups: control group n=ı 49 (coronary angiography normal), case group n=25ı (CAD prescnt). Transferrio saturat ion was categorized as :5:10% and > 10%. Serum ferri tin !eve! was grouped as <200ng/ml and 2!200ng/ml. A nonsignificant weak negative relation (p=0.5) was idcntified between serum ferrit in level and CAD by multivariate logistic regression analysis. No significanı relation (P=0.4) was noted between serum transferrio saturation and CAD. The results did not gain statistical significance for both transferrio saturation and ferritin !eve! when patients with high LDL-choJesterol !eve! were included in the model. Thus, our results do not support the hypothesis on a relation between serum iron stoı·es and CAD.

Keywords: Coronary artery disease, ferritin, transferrio saturation.

How to cite this article
Abdurrahman OĞUZHAN, Halil Lütfi KISACIK, Koray GÜRSEL, Kurtuluş ÖZDEMİR, Selime AYAZ, İsmet HİSAR, Ahmet AVCI, Siber GÖKSEL. Serum Transferrin Saturation and Ferritin Level as a Risk Factor in Coronary Artery Disease. Turk Kardiyol Dern Ars. 1998; 26(3): 142-144
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