Is there a relationship between slow coronary flow and normal to mildly impaired renal function? [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2016; 44(3): 207-214 | DOI: 10.5543/tkda.2015.02428

Is there a relationship between slow coronary flow and normal to mildly impaired renal function?

Ali Kemal Çabuk1, Gizem Çabuk2, Murat Karamanlıoğlu3, Kader Eliz Uzel4, Sezen Bağlan Uzunget5, Ömer Faruk Aslantürk6, Ümit Güray7
1Department Of Cardiyology, Tepecik Training And Research Hospital, Izmir, Turkey
2Department Of Cardiology, Buca Seyfi Demirsoy State Hospital, Izmir, Turkey
3Department Of Cardiology, Ataturk Chest Diseases And Chest Surgery Training And Research Hospital, Ankara, Turkey
4Department Of Cardiology, Besni State Hospital, Adıyaman, Turkey
5Department Of Cardiology, Sincan State Hospital, Ankara, Turkey
6Department Of Cardiology, Kuşadası State Hospital, Aydın, Turkey
7Department Of Cardiology, Numune Training And Research Hospital, Ankara, Turkey


OBJECTIVE
The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation is more effective at estimating glomerular filtration rate (GFR) than the Modification of Diet in Renal Disease (MDRD) equation, particularly in patients with mildly impaired renal function. Recent studies have demonstrated, using the Cockroft-Gault and MDRD formulas, a significant correlation between slow coronary flow (SCF) and normal to mildly impaired renal function. However, these studies had some limitations. The aim of the present study was to investigate the relationship between SCF and normal to mildly impaired renal function using the CKD-EPI equation.

METHODS
A total of 370 patients were included, 172 with normal coronary flow (NCF) and 198 with SCF. All participants had normal to mildly impaired renal function. Both the CKDEPI and MDRD formulas were used to calculated estimated glomerular filtration rate (eGFR), which was compared between groups.

RESULTS
No significant difference in mean values of eGFR was found between the NCF and SCF groups (CKD-EPI: 92.9±14.7 vs 92.7±14.2, p=0.72; MDRD: 89.5±19.5 vs 88.2±17.0, p=0.70, respectively). Among patients with eGFR(MDRD) ≥90 mL/ min/1.73 m2, mean eGFR levels were lower among patients with SCF (107.0±12.7 vs 102.7±10.0, p=0.02).

CONCLUSION
No correlation was found between SCF and normal to mildly impaired renal function.

Keywords: Kidney dysfunction, glomerular filtration rate; coronary slow flow

How to cite this article
Ali Kemal Çabuk, Gizem Çabuk, Murat Karamanlıoğlu, Kader Eliz Uzel, Sezen Bağlan Uzunget, Ömer Faruk Aslantürk, Ümit Güray. Is there a relationship between slow coronary flow and normal to mildly impaired renal function?. Turk Kardiyol Dern Ars. 2016; 44(3): 207-214

Corresponding Author: Ali Kemal Çabuk, Türkiye
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